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341326 Fatty Acid Synthase Inhibitor, Cpd 10v - CAS 1027354-00-2 - Calbiochem

The Fatty Acid Synthase Inhibitor, Cpd 10v, also referenced under CAS 1027354-00-2, controls the biological activity of Fatty. This small molecule/inhibitor is primarily used for Cancer applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 7-chloro-4-hydroxy-3-(2ʹ-methoxybiphenyl-3-yl)-2-oxo-1,2-dihydroquinoline-6-carbonitrile, FAS inhibitor

341326
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1027354-00-2C₂₃H₁₅ClN₂O₃
Description
Overview

This product has been discontinued.



A hydroxyquinolinone derivative that acts as a potent reversible inhibitor of type 1 fatty acid synthase (FAS) (IC50 = 19 nM) when enzyme activity is monitored by following the synthesis of free coenzyme A (CoA-SH).
Catalogue Number341326
Brand Family Calbiochem®
Synonyms7-chloro-4-hydroxy-3-(2ʹ-methoxybiphenyl-3-yl)-2-oxo-1,2-dihydroquinoline-6-carbonitrile, FAS inhibitor
References
ReferencesRivkin, A., et al. 2006. J. med. Chem. 16, 4620.
Product Information
CAS number1027354-00-2
FormWhite solid
Hill FormulaC₂₃H₁₅ClN₂O₃
Chemical formulaC₂₃H₁₅ClN₂O₃
Structure formula ImageStructure formula Image
Applications
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Regulatory Review
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
341326 0

Documentation

Fatty Acid Synthase Inhibitor, Cpd 10v - CAS 1027354-00-2 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Fatty Acid Synthase Inhibitor, Cpd 10v - CAS 1027354-00-2 - Calbiochem Certificates of Analysis

TitleLot Number
341326

References

Reference overview
Rivkin, A., et al. 2006. J. med. Chem. 16, 4620.

Brochure

Title
New Products: Volume 3, 2012
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-April-2012 JSW
Synonyms7-chloro-4-hydroxy-3-(2ʹ-methoxybiphenyl-3-yl)-2-oxo-1,2-dihydroquinoline-6-carbonitrile, FAS inhibitor
DescriptionA hydroxyquinolinone derivative that acts as a potent reversible inhibitor of type 1 fatty acid synthase (FAS) (IC50 = 19 nM) when enzyme activity is monitored by following the synthesis of free coenzyme A (CoA-SH).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number1027354-00-2
Chemical formulaC₂₃H₁₅ClN₂O₃
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (50 mg/ml; clear, colorless solution)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Regulatory Review
ReferencesRivkin, A., et al. 2006. J. med. Chem. 16, 4620.