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341214 Extracellular Death Factor Peptide, NNWNN

341214
  
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₇H₃₆N₁₀O₁₀
Description
Overview

This product has been discontinued.





A pentapeptide that acts as an essential extracellular death factor (EDF) for the toxin-antitoxin module mazEF-mediated cell death in E. coli cultures. The killing activity of EDF is shown to be mazEF-dependent at low concentrations, but becomes more and more mazEF-independent at concentrations higher than 200 ng/ml. Sequence analysis of E. coli genome reveals the gene products of zwf (coding glucose-6-phosphate dehydrogenase) and ygeO as likely precursors of EDF.
Catalogue Number341214
Brand Family Calbiochem®
SynonymsH-Asn-Asn-Trp-Asn-Asn-OH
References
ReferencesKolodkin-Gal, I., et al. 2007. Science 318, 652.
Product Information
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₂₇H₃₆N₁₀O₁₀
Chemical formulaC₂₇H₃₆N₁₀O₁₀
Hygroscopic Hygroscopic
Applications
Biological Information
Purity≥97% by HPLC
Physicochemical Information
Peptide SequenceH₂N-Asn-Asn-Trp-Asn-Asn-CO₂H
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
S PhraseS: 22-24/25-36/37

Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing and gloves.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
341214 0

Documentation

Extracellular Death Factor Peptide, NNWNN Certificates of Analysis

TitleLot Number
341214

References

Reference overview
Kolodkin-Gal, I., et al. 2007. Science 318, 652.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-November-2008 RFH
SynonymsH-Asn-Asn-Trp-Asn-Asn-OH
DescriptionA pentapeptide that acts as an essential extracellular death factor (EDF) for the toxin-antitoxin module mazEF-mediated cell death in E. coli cultures. The killing activity of EDF is shown to be mazEF-dependent at low concentrations, but becomes more and more mazEF-independent at concentrations higher than 200 ng/ml. Sequence analysis of E. coli genome reveals the gene products of zwf (coding glucose-6-phosphate dehydrogenase) and ygeO as likely precursors of EDF.
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₂₇H₃₆N₁₀O₁₀
Peptide SequenceH₂N-Asn-Asn-Trp-Asn-Asn-CO₂H
Purity≥97% by HPLC
SolubilityH₂O (5 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesKolodkin-Gal, I., et al. 2007. Science 318, 652.