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324905 Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem

A cell-permeable antitumor antibiotic.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4ʹ-Epidoxorubicin, HCl

Primary Target: Antitumor antibiotic
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
56390-09-1C₂₇H₂₉NO₁₁ · HCl
Description
Overview

This product has been discontinued.



A cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin (Cat. No. 324380) that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.
Catalogue Number324905
Brand Family Calbiochem®
Synonyms4ʹ-Epidoxorubicin, HCl
References
ReferencesLuck, H.J., et al. 1996. Semin. Oncol. 23, 33.
Sandri, M.I., et al. 1996. Br. J. Cancer 73, 1518.
Boddy, A.V., et al. 1995. Eur. J. Cancer 31A, 69.
Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol. 35, 257.
Product Information
CAS number56390-09-1
ATP CompetitiveN
FormOrange-red solid
Hill FormulaC₂₇H₂₉NO₁₁ · HCl
Chemical formulaC₂₇H₂₉NO₁₁ · HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetAntitumor antibiotic
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSQI9295750
Safety Information
R PhraseR: 20/21/22-40

Harmful by inhalation, in contact with skin and if swallowed.
Limited evidence of a carcinogenic effect.
S PhraseS: 22-36

Do not breathe dust.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
324905 0

Documentation

Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem Certificates of Analysis

TitleLot Number
324905

References

Reference overview
Luck, H.J., et al. 1996. Semin. Oncol. 23, 33.
Sandri, M.I., et al. 1996. Br. J. Cancer 73, 1518.
Boddy, A.V., et al. 1995. Eur. J. Cancer 31A, 69.
Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol. 35, 257.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-May-2008 RFH
Synonyms4ʹ-Epidoxorubicin, HCl
DescriptionA cell-permeable, antitumor antibiotic. A stereoisomer of doxorubicin that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.
FormOrange-red solid
CAS number56390-09-1
RTECSQI9295750
Chemical formulaC₂₇H₂₉NO₁₁ · HCl
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityH₂O (1 mg/ml)
Storage Protect from light
+2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful & Carcinogenic / Teratogenic
Merck USA index14, 3623
ReferencesLuck, H.J., et al. 1996. Semin. Oncol. 23, 33.
Sandri, M.I., et al. 1996. Br. J. Cancer 73, 1518.
Boddy, A.V., et al. 1995. Eur. J. Cancer 31A, 69.
Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol. 35, 257.