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30967 Diisopropylfluorophosphate

Diisopropylfluorophosphate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DFP

30967
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
55-91-4C₆H₁₄FO₃P
Description
Overview

This product has been discontinued.



Please refer to our complete listing of cholinesterase inhibitors for possible alternatives.






Serine protease inhibitor. A potent, irreversible inactivator of acetylcholinesterase that can cross the blood-brain barrier. Selectively blocks T cell receptor-triggered programmed cell death in murine T cell hybridoma and in activated peripheral T cells.
Effective concentration: 100 µM; t½ = 1 h at pH 7.5. Use caution upon opening. May develop pressure. Use only if colorless.
Density: 1.055 g/ml
Catalogue Number30967
Brand Family Calbiochem®
SynonymsDFP
References
ReferencesOshikawa, K., et al. 2000. Biosci. Biotechnol. Biochem. 64, 2186.
Takahashi, M., et al. 1994. Mol. Reprod. Dev. 38, 310.
Sarin, A., et al. 1993. J. Exp. Med. 178, 1693.
Sikder, A.K., et al. 1993. J. Pharmacol. Sci. 82, 258.
Ho, K., and Hoskins, B. 1983. Drug Chem. Toxicol. 6, 421.
Cohen, J.A., et al. 1967. Methods Enzymol. 11, 686.
Product Information
CAS number55-91-4
FormColorless liquid
Hill FormulaC₆H₁₄FO₃P
Chemical formulaC₆H₁₄FO₃P
Structure formula ImageStructure formula Image
Applications
Biological Information
Purity≥98% by P-NMR
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSTE5075000
Safety Information
R PhraseR: 26/27/28-34

Very toxic by inhalation, in contact with skin and if swallowed.
Causes burns.
S PhraseS: 26-28-36/37/39-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Highly Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsNote: use caution while opening; may develop pressure. Use only if colorless. Following reconstitution, aliquot and freeze (-70°C). Aqueous and DMSO stock solutions are highly unstable.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
30967 0

Documentation

Diisopropylfluorophosphate Certificates of Analysis

TitleLot Number
30967

References

Reference overview
Oshikawa, K., et al. 2000. Biosci. Biotechnol. Biochem. 64, 2186.
Takahashi, M., et al. 1994. Mol. Reprod. Dev. 38, 310.
Sarin, A., et al. 1993. J. Exp. Med. 178, 1693.
Sikder, A.K., et al. 1993. J. Pharmacol. Sci. 82, 258.
Ho, K., and Hoskins, B. 1983. Drug Chem. Toxicol. 6, 421.
Cohen, J.A., et al. 1967. Methods Enzymol. 11, 686.

Brochure

Title
Alzheimer's Disease Brochure & Technical Guide
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-September-2008 JSW
SynonymsDFP
DescriptionSerine protease inhibitor. Irreversibly inactivates acetylcholinesterase. Selectively blocks T cell receptor-triggered programmed cell death in murine T-cell hybridoma and in activated peripheral T-cells. Commonly used at a concentration of 100 µM. Density: 1.055 g/ml.
FormColorless liquid
Intert gas (Yes/No) Packaged under inert gas
CAS number55-91-4
RTECSTE5075000
Chemical formulaC₆H₁₄FO₃P
Structure formulaStructure formula
Purity≥98% by P-NMR
SolubilityIsopropanol (50 mg/ml)
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsNote: use caution while opening; may develop pressure. Use only if colorless. Following reconstitution, aliquot and freeze (-70°C). Aqueous and DMSO stock solutions are highly unstable.
Toxicity Highly Toxic
Merck USA index14, 5176
ReferencesOshikawa, K., et al. 2000. Biosci. Biotechnol. Biochem. 64, 2186.
Takahashi, M., et al. 1994. Mol. Reprod. Dev. 38, 310.
Sarin, A., et al. 1993. J. Exp. Med. 178, 1693.
Sikder, A.K., et al. 1993. J. Pharmacol. Sci. 82, 258.
Ho, K., and Hoskins, B. 1983. Drug Chem. Toxicol. 6, 421.
Cohen, J.A., et al. 1967. Methods Enzymol. 11, 686.