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233155 Cleland’s Reagent - CAS 3483-12-3 - Calbiochem

A protective agent for SH groups. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. Does not contain waxy surfactant found in many other preparations. Oxidized dithio

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MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Dithiothreitol, DTT

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Overview

Key Spec Table

CAS #Empirical Formula
3483-12-3C₄H₁₀O₂S₂

Products

Catalogue NumberPackaging Qty/Pack
233155-100GM Glass bottle 100 gm
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233155-10GM Plastic ampoule 10 gm
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233155-1KG Glass bottle 1 kg
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233155-25GM Glass bottle 25 gm
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233155-500GM Glass bottle 500 gm
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Description
OverviewA protective agent for SH groups. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. Does not contain waxy surfactant found in many other preparations.
Oxidized dithiothreitol: ≤0.5%.
Catalogue Number233155
Brand Family Calbiochem®
SynonymsDithiothreitol, DTT
References
ReferencesGailis, L. 1994. Eur. J. Pharmacol. 292, 39.
Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
Cleland, W.W. 1964. Biochemistry 3, 480.
Product Information
CAS number3483-12-3
FormWhite to off-white powder
Hill FormulaC₄H₁₀O₂S₂
Chemical formulaC₄H₁₀O₂S₂
Quality LevelMQ100
Biological Information
Purity≥97% by titration
Physicochemical Information
ContaminantsHeavy metals: ≤1 ppm
Heavy metals<1 ppm
Safety Information according to GHS
RTECSEK1610000
Safety Information
R PhraseR: 22-36/38

Harmful if swallowed.
Irritating to eyes and skin.
S PhraseS: 36-26

Wear suitable protective clothing.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
233155-100GM 07790788054274
233155-10GM 04055977217698
233155-1KG 04055977217681
233155-25GM 04055977217711
233155-500GM 04055977217735