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220551 Chloramphenicol - CAS 56-75-7 - Calbiochem

Chloramphenicol, CAS 56-75-7, is a synthetic bacteriostatic antibiotic that inhibits the translation of RNA by blocking the peptidyltransferase reaction on ribosomes.

Chloramphenicol - CAS 56-75-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: trasnslation of RNA
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
56-75-7C₁₁H₁₂Cl₂N₂O₅
Description
OverviewSynthetic bacteriostatic antibiotic that inhibits the translation of RNA by blocking the peptidyltransferase reaction on ribosomes.
Catalogue Number220551
Brand Family Calbiochem®
References
ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
Saltarelli, M.J., et al. 1993. Virol. 197, 35.
Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.
Product Information
CAS number56-75-7
FormGrayish to off-white crystalline powder
Hill FormulaC₁₁H₁₂Cl₂N₂O₅
Chemical formulaC₁₁H₁₂Cl₂N₂O₅
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Biological activityPotency: ≥970 µg/mg
Primary Targettrasnslation of RNA
Purity≥97% by Assay
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSAB6825000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
220551 0

Documentation

Chloramphenicol - CAS 56-75-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Chloramphenicol - CAS 56-75-7 - Calbiochem Certificates of Analysis

TitleLot Number
220551

References

Reference overview
Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
Saltarelli, M.J., et al. 1993. Virol. 197, 35.
Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.

Brochure

Title
Antibiotics Profiler
Bulk Product Guide
Overnight Express Autoinduction Systems
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-January-2014 JSW
DescriptionSynthetic bacteriostatic antibiotic that inhibits the translation of RNA to protein by binding to the 50S ribosomal subunit, blocking the peptidyl transferase reaction. Chloramphenicol resistance is encoded by the resistance gene cat, whose product, chloramphenicol acetyltransferase, inactivates the antibiotic via acetylation. Typically used at 30-50 µg/ml for selection of chloramphenicol-resistant Escherichia coli.
FormGrayish to off-white crystalline powder
CAS number56-75-7
RTECSAB6825000
Chemical formulaC₁₁H₁₂Cl₂N₂O₅
Structure formulaStructure formula
Purity≥97% by Assay
Biological activityPotency: ≥970 µg/mg
SolubilityEthanol, Methanol (35 mg/ml), or H₂O (2.5 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
Merck USA index14 2077
ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
Saltarelli, M.J., et al. 1993. Virol. 197, 35.
Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.