264158 Sigma-AldrichCaspase Modulator II, 1541B - Calbiochem
Caspase Modulator II, 1541B primarily used in Inhibition.
More>> Caspase Modulator II, 1541B primarily used in Inhibition. Less<<Caspase Modulator II, 1541B - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Procaspase-3 Activator III, 8-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid-(3-imidazo[1,2-a]pyridin-2-yl-phenyl)-amide, Caspase-3 Inhibitor XVI
Recommended Products
Overview
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Key Spec Table
| Empirical Formula |
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| C₂₃H₁₅N₃O₄ |
Products
| Catalogue Number | Packaging | Qty/Pack | |
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| 264158-10MG | 10 mg |
| Description | |
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| Overview | A cell-permeable, of 8-Hydroxy analog 1541 (Cat. No. 529662) that is shown to selectively activate procaspase-3 (EC50 = 1.3 µM), but not procaspase-6. Both 1541 and 1541B are shown to effectively induce apoptosis in various cancer cell lines with comparable potencies, indicating that caspase-3 activation alone is as effective in cell death induction as simultaneous activations of caspase-3/-6 among cells tested. 1541B is expected to inhibit the activity of mature/active caspase-3 and exhibit reduced procaspase-3 activation at high concentrations. |
| Catalogue Number | 264158 |
| Brand Family | Calbiochem® |
| Synonyms | Procaspase-3 Activator III, 8-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid-(3-imidazo[1,2-a]pyridin-2-yl-phenyl)-amide, Caspase-3 Inhibitor XVI |
| References | |
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| References | Wolan, D.W., et al. 2009. Science 326, 853. |
| Product Information | |
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| Form | Pale yellow solid |
| Hill Formula | C₂₃H₁₅N₃O₄ |
| Chemical formula | C₂₃H₁₅N₃O₄ |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥95% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 264158-10MG | 04055977198492 |
Documentation
Caspase Modulator II, 1541B - Calbiochem SDS
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Caspase Modulator II, 1541B - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 264158 |
References
| Reference overview |
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| Wolan, D.W., et al. 2009. Science 326, 853. |