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208731 Calpain Substrate II, Fluorogenic - CAS 94367-20-1 - Calbiochem

Cyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Suc-LY-AMC

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208731
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
208731-25MG Plastic ampoule 25 mg
Description
OverviewCyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2. Also suitable for measuring the peptidase activity of the 20S proteasome. Typical concentrations range from 10 - 100 µM, depending on assay conditions.
Catalogue Number208731
Brand Family Calbiochem®
SynonymsSuc-LY-AMC
References
ReferencesSeol, J.H., et al. 1989. FEBS Lett. 247, 197.
Woo, K.M., et al. 1989. J. Biol. Chem. 264, 2088.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.
Product Information
CAS number94367-20-1
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₂₉H₃₁N₃O₇
Chemical formulaC₂₉H₃₁N₃O₇
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetCalpain -1 and -2
Purity≥95% by TLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide SequenceSuc-Leu-Tyr-AMC
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
208731-25MG 04055977202748

Documentation

Calpain Substrate II, Fluorogenic - CAS 94367-20-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Calpain Substrate II, Fluorogenic - CAS 94367-20-1 - Calbiochem Certificates of Analysis

TitleLot Number
208731

References

Reference overview
Seol, J.H., et al. 1989. FEBS Lett. 247, 197.
Woo, K.M., et al. 1989. J. Biol. Chem. 264, 2088.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-May-2008 RFH
SynonymsSuc-LY-AMC
DescriptionFluorogenic substrate for the quantitative determination of porcine calpain I and II activity. Also serves as a substrate for other proteases including proteasome. (excitation wavelength: 380 nm; emission wavelength: 460 nm)
FormOff-white solid
CAS number94367-20-1
Chemical formulaC₂₉H₃₁N₃O₇
Peptide SequenceSuc-Leu-Tyr-AMC
Purity≥95% by TLC
SolubilityDMSO
Storage Protect from moisture
Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesSeol, J.H., et al. 1989. FEBS Lett. 247, 197.
Woo, K.M., et al. 1989. J. Biol. Chem. 264, 2088.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.