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203702 Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhBDNF

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Overview

Replacement Information

Key Spec Table

Purity
≥97% by HPLC
Description
OverviewRecombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons. Structurally and functionally related to nerve growth factor. Its actions are mediated via the TrkB receptor.
Catalogue Number203702
Brand Family Calbiochem®
SynonymsrhBDNF
References
ReferencesErickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
Leibrock, J., et al. 1989. Nature 341, 149.
Product Information
FormLyophilized
Quality LevelMQ100
Applications
Biological Information
Biological activitySupports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC₅₀ = 50 ng/ml)
Purity≥97% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
203702 0

Documentation

Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli SDS

Title

Safety Data Sheet (SDS) 

Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
203702

References

Reference overview
Erickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
Leibrock, J., et al. 1989. Nature 341, 149.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-February-2019 JSW
SynonymsrhBDNF
DescriptionRecombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons in the central nervous system. Sequence analysis indicates that brain derived neurotrophic factor is structurally and functionally related to nerve growth factor. mRNA for brain derived neurotrophic factor is found predominantly in the central nervous system, whereas mRNA for nerve growth factor is also found in many non-CNS tissues.
FormLyophilized
Purity≥97% by HPLC
Biological activitySupports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC₅₀ = 50 ng/ml)
SolubilityReconstitute to a concentration of ≥10 µg/ml with sterile distilled H₂O or aqueous buffers. For more dilute solutions, add a stabilizing protein such as 0.1% BSA or HSA.
Storage Protect from moisture
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
Toxicity Standard Handling
Merck USA index14, 6487
ReferencesErickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
Leibrock, J., et al. 1989. Nature 341, 149.