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05-23-3831 BQ-123, Sodium Salt - CAS - Calbiochem

A highly potent, selective, and competitive ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus Ki = 2.5 µM for ETB).

BQ-123, Sodium Salt - CAS - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: ETA (endothelin) receptor antagonist
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₃₁H₄₁N₆O₇ · Na

Products

Catalogue NumberPackaging Qty/Pack
05-23-3831-1MG Plastic ampoule 1 mg
Description
OverviewA highly potent, selective, and competitive ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus Ki = 2.5 μM for ETB).
Catalogue Number05-23-3831
Brand Family Calbiochem®
References
ReferencesNambi, P., et al. 1996. J. Pharmacol. Exp. Ther. 277, 1567.
Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.
Product Information
ATP CompetitiveN
FormWhite solid
FormulationSupplied as a sodium salt. Sold on the basis of peptide content.
Hill FormulaC₃₁H₄₁N₆O₇ · Na
Chemical formulaC₃₁H₄₁N₆O₇ · Na
Hygroscopic Hygroscopic
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary TargetETA (endothelin) receptor antagonist
Primary Target K<sub>i</sub>40 nM for ETA versus 2.5 µM for ETB
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceCyclo(D-Asp-Pro-D-Val-Leu-D-Trp, Na)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
05-23-3831-1MG 04055977226812

Documentation

BQ-123, Sodium Salt - CAS - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

BQ-123, Sodium Salt - CAS - Calbiochem Certificates of Analysis

TitleLot Number
05-23-3831

References

Reference overview
Nambi, P., et al. 1996. J. Pharmacol. Exp. Ther. 277, 1567.
Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision31-May-2011 JSW
DescriptionA highly potent and selective ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus 2.5 µM for ETB).
FormWhite solid
FormulationSupplied as a sodium salt. Sold on the basis of peptide content.
Chemical formulaC₃₁H₄₁N₆O₇ · Na
Peptide SequenceCyclo(D-Asp-Pro-D-Val-Leu-D-Trp, Na)
Purity≥95% by HPLC
SolubilityH₂O (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesNambi, P., et al. 1996. J. Pharmacol. Exp. Ther. 277, 1567.
Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.