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ABS796 Anti-phospho-HER4 Antibody (Tyr1162)

Detect HER4 using this rabbit polyclonal Anti-phospho-HER4 Antibody, Cat. No. ABS796, validated for use in Western Blotting, Immunohistochemistry, and Immunocytochemistry.

Anti-phospho-HER4 Antibody (Tyr1162) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: General Post-translation Modification Gene Symbol: ERBB4 UniProt Number: Q15303
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ABS796
80 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHC, ICCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS796
DescriptionAnti-phospho-HER4 Antibody (Tyr1162)
Alternate Names
  • ERBB4
  • HER4
  • Receptor tyrosine-protein kinase erbB-4
  • Proto-oncogene-like protein c-ErbB-4
  • Tyrosine kinase-type cell surface receptor HER4
  • p180erbB4
  • ERBB4 intracellular domain
  • s80HER4
Background InformationReceptor tyrosine-protein kinase erbB-4, also known as, Proto-oncogene-like protein c-ErbB-4 (4ICD or E4ICD), and encoded by the gene names Erbb4 or Tyro-2, plays an essential role as cell surface receptor for neuregulins. ERBB4 regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. ERBB4 is preferentially expressed in the developing nervous system. It exhibits distinct and highly regionalized patterns of expression in the adult brain, where it is mainly found in the reticular nucleus of the thalamus.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS with 0.09% (W/V) sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect HER4 using this rabbit polyclonal Anti-phospho-HER4 Antibody, Cat. No. ABS796, validated for use in Western Blotting, Immunohistochemistry, and Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunocytochemistry
Application NotesImmunohistochemistry Analysis (IHC): A 1:10-50 dilution from a representative lot detected HER4 in human cancer tissue.

Immunocytochemistry Analysis (ICC): A 1:10-50 dilution from a representative lot detected HER4 in MCF-7 cells.
Biological Information
ImmunogenKLH-conjugated synthetic peptide corresponding to human PGK1 phosphorylated at Tyr1162.
EpitopePhosphorylated Tyr1162
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • ERBB4
Modifications
  • Phosphorylation
Purification MethodAffinity
UniProt Number
Molecular Weight~160 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in untreated and EGF treated A431 cell lysates.

Western Blotting Analysis (WB): A 1:1000 dilution of this antibody detected HER4 in untreated and EGF treated A431 cell lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Packaging Information
Material Size80 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABS796 04055977157208

Documentation

Anti-phospho-HER4 Antibody (Tyr1162) SDS

Title

Safety Data Sheet (SDS) 

Anti-phospho-HER4 Antibody (Tyr1162) Certificates of Analysis

TitleLot Number
Anti-phospho-HER4 (Tyr1162) -QVP1411204 QVP1411204
Anti-phospho-HER4 (Tyr1162) Polyclonal Antibody VP1709201
Anti-phospho-HER4 (Tyr1162) Polyclonal Antibody VP1809130

Brochure

Title
NPI Flyer- Epigenetics and Nuclear Function Feature
New Products - Antibodies, Small Molecule, Inhibitors

Technical Info

Title
White Paper: Further considerations of antibody validation and usage.