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ABT131 Anti-PTRF/cavin-1 Antibody

Anti-PTRF/cavin-1 Antibody detects level of PTRF/cavin-1 & has been published & validated for use in Western Blotting, IHC(P).

Anti-PTRF/cavin-1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: ECM Proteins Gene Symbol: PTRF UniProt Number: Q6NZI2
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ABT131
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT131
DescriptionAnti-PTRF/cavin-1 Antibody
Alternate Names
  • Polymerase I and transcript release factor
  • Cavin-1
Background InformationPolymerase I and transcript release factor (PTRF), also known as “cavin-1,” is a small cytoplasmic protein, which interacts with caveolin-1 to assemble specialized membrane invaginations (or caveolae), in various types of cells. Caveolae house specific proteins and lipids and play a central role in cell signaling and endocytosis. PTRF may also play a role in metabolism. Mice lacking functional PTRF are affected by hyperinsulinemia and glucose intolerance. In addition, PTRF may play a role in prostate cancer.
References
Product Information
FormatAffinity Purified
Control
  • Human lung tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-PTRF/cavin-1 Antibody detects level of PTRF/cavin-1 & has been published & validated for use in Western Blotting, IHC(P).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:500 dilution from a representative lot detected PTRF/cavin-1 in mouse cardiac tissue and mouse alveoli tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the Coiled Coil domain of human PTRF/cavin-1.
EpitopeCoiled Coil domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the Coiled Coil domain of PTRF/cavin-1.
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PTRF
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~60 kDa, ~43 kDa observed. Three isoforms at 43 kDa, 33 kDa, and 23 kDa are known to exist. This protein was observed at ~60 kDa by an independent laboratory due to post-translational modification (Hill, M. M., et al. (2008). Cell. 132(1):113-124.).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in human lung tissue lysate.

Western Blot Analysis: 1 mg/mL of this antibody detected PTRF/cavin-1 in 10 mg of human lung tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABT131 04053252522826

Documentation

Anti-PTRF/cavin-1 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-PTRF/cavin-1 Antibody Certificates of Analysis

TitleLot Number
Anti-PTRF/cavin-1 2480964
Anti-PTRF/cavin-1 - 2262716 2262716
Anti-PTRF/cavin-1 - 2564875 2564875
Anti-PTRF/cavin-1 - 3301908 3301908
Anti-PTRF/cavin-1 - 3387573 3387573
Anti-PTRF/cavin-1 - 3607090 3607090
Anti-PTRF/cavin-1 - 3733790 3733790
Anti-PTRF/cavin-1 - Q2034344 Q2034344
Anti-PTRF/cavin-1 -2610947 2610947
Anti-PTRF/cavin-1 -2659600 2659600
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