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AB3503-I Anti-PDX-1 Antibody

This Anti-PDX-1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of PDX-1.

Anti-PDX-1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: PDX1, IPF1, STF1 UniProt Number: P52945
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AB3503-I
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB3503-I
DescriptionAnti-PDX-1 Antibody
Alternate Names
  • Pancreas/duodenum homeobox protein 1
  • PDX-1
  • Glucose-sensitive factor
  • GSF
  • Insulin promoter factor 1
  • IPF-1
  • Insulin upstream factor 1
  • IUF-1
  • Islet/duodenum homeobox-1
  • IDX-1
  • Somatostatin-transactivating factor 1
  • STF-1
Background InformationPancreatic and duodenal homeobox 1, also known as PDX1, and Insulin promoter factor 1 is a human gene. This islet-specific protein activates transcription of the insulin andsomatostatin genes. It is a key regulator of islet peptide hormone expressionn and also plays an essential role in pancreatic development. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-PDX-1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of PDX-1.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected pdx-1 in the islets of Langerhans of human and mouse pancreas.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to region amino acids 90-120 of human PDX-1.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityRecognizes PDX-1
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PDX1
  • IPF1
  • STF1
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~38 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse pancreatic beta cell tissue lysate.

Western Blotting Analysis: A 1:4,000 dilution of this antibody detected PDX-1 in mouse pancreatic beta cell tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB3503-I 04055977052817