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ABT41 Anti-Myosin XIX (Myo19) Antibody

Anti-Myosin XIX (Myo19) Antibody detects level of Myosin XIX (Myo19) & has been published & validated for use in IH(P).

Anti-Myosin XIX (Myo19) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: MYO19, MYOHD1 UniProt Number: Q96H55
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ABT41
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, CaIH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT41
DescriptionAnti-Myosin XIX (Myo19) Antibody
Alternate Names
  • Myosin-XIX
  • Myosin head domain-containing protein 1
Background InformationMyosin XIX (Myo19) is the founding member of a novel class of myosin that associates with mitochondria. Both endogenous Myo19 and GFP-Myo19 exihibit localization to mitochondria. Myosins are actin-based motor molecules with ATPase activity. Myo19 is involved in actin-based mitochondrial motility. Myo19 mRNA is expressed in multiple tissues, and antibodies to human Myo19 detect an approximately 109 kDa band in multiple cell lines.
References
Product Information
FormatAffinity Purified
Control
  • Human cardiac muscle tissue
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Myosin XIX (Myo19) Antibody detects level of Myosin XIX (Myo19) & has been published & validated for use in IH(P).
Key Applications
  • Immunohistochemistry (Paraffin)
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Myosin XIX (Myo19).
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Canine
Species Reactivity NoteDemonstrated to react with Human.
Predicted to react with Canine based on 100% sequence homology. Other homologies: Rat and Mouse (92% sequence homology).
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • MYO19
  • MYOHD1
Purification MethodAffinity Purfied
UniProt Number
UniProt SummaryFUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility.

SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton. Mitochondrion outer membrane. Note: Probably associated with the outer membrane via its N-terminal mitochondrial targeting region. TISSUE SPECIFICITY: Widely expressed in multiple tissues and cell lines.

SEQUENCE SIMILARITIES: Contains 2 IQ domains.

Contains 1 myosin head-like domain.

SEQUENCE CAUTION: The sequence BAD92272.1 differs from that shown. Reason: Erroneous initiation.
Molecular Weight109 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in human cardiac muscle tissue.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Myosin XIX (Myo19) in human cardiac muscle tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABT41 04053252420627