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MABN92-AF647 Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate is an antibody against AIF1 for use in Immunofluorescence.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Inflammation & Autoimmune Mechanisms Gene Symbol: AIF1, G1, IBA1 UniProt Number: P55008
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MABN92-AF647
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RIFMAlexaFluor®647Monoclonal Antibody
Description
Catalogue NumberMABN92-AF647
DescriptionAnti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate
Alternate Names
  • Allograft inflammatory factor 1
  • AIF-1
  • Daintain
  • Interferon gamma responsive transcript
  • Ionized calcium-binding adapter molecule 1
  • Protein G1
Background InformationAllograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.
References
Product Information
FormatAlexaFluor®647
PresentationPurified mouse monoclonal IgG1κ antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate is an antibody against AIF1 for use in Immunofluorescence.
Key Applications
  • Immunofluorescence
Application NotesThe unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.
Biological Information
ImmunogenLinear peptide corresponding to human Iba1/AIF1.
Clone20A12.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • AIF1
  • G1
  • IBA1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~17 kDa observed.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunofluorescence in human spleen tissue.

Immunofluorescence Analysis: A 1:50 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN92-AF647 04055977335262

Documentation

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 647 Conjugate Certificates of Analysis

TitleLot Number
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 647 Conjugate 3020520
Anti-Iba1/AIF1, clone 20A12.1, -Q2669709 Q2669709
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 647 Conjugate - 3192046 3192046
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 647 Conjugate - 3423273 3423273
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 647 Conjugate - 3724623 3724623
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 647 Conjugate - 3887046 3887046
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 647 Conjugate - 4083728 4083728
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 647 Conjugate Monoclonal Antibody 3117839