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ABS445 Anti-Caspase-5 Antibody

Detect Caspase 5 using this rabbit polyclonal antibody, Anti-Caspase-5 Antibody validated for use in western blotting, ICC & Immunofluorescence.

Anti-Caspase-5 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: CASP5, ICH3 UniProt Number: P51878
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ABS445
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ICC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS445
DescriptionAnti-Caspase-5 Antibody
Alternate Names
  • Caspase-5
  • CASP-5
  • ICE(rel)-III
  • Protease ICH-3
  • Protease TY
  • Caspase-5 subunit p202.Caspase-5 subunit p10
Background InformationCaspase-5 (CASP5) is a member of the peptidase C14A family that can be divided into the apoptotic and inflammatory caspase subfamilies. Members of this subfamily include caspase-1, -4, -5, and -12. When activated, these caspases result in the cleavage and activation of proinflammatory cytokines such as IL-1beta and IL-18. Caspase-5 is expressed in barely detectable amounts in most tissues except brain, with highest levels being found in lung, liver and skeletal muscle. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts.
References
Product Information
FormatAffinity Purified
Control
  • Ramos cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Caspase 5 using this rabbit polyclonal antibody, Anti-Caspase-5 Antibody validated for use in western blotting, ICC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunocytochemistry
  • Immunofluorescence
Application NotesImmunocytochemistry Analysis: 2 µg/mL from a representative lot detected Caspase-5 in P815 cells.

Immunofluorescence Analysis: 2 µg/mL from a representative lot detected Caspase-5 in P815 cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the intermediate domain of human Caspase-5.
EpitopeIntermediate domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the intermediate domain of Caspase-5.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • CASP5
  • ICH3
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~48 kDa observed. Uncharacterized bands may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Ramos cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected Caspase-5 in Ramos cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABS445 04053252878824