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AB5314 Anti-Carboxypeptidase H Antibody, CT

Anti-Carboxypeptidase H Antibody, C-terminus is an antibody against Carboxypeptidase H for use in IP, WB & IC.

Anti-Carboxypeptidase H Antibody, CT MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Metabolism Research Sub-Category: Enzymes & Biochemistry Gene Symbol: CPE, CPH, EC 3.4.17.10 UniProt Number: P16870
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AB5314
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RIP, WB, ICCRbSerumPolyclonal Antibody
Description
Catalogue NumberAB5314
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Carboxypeptidase H Antibody, CT
Alternate Names
  • CPH
  • Carboxypeptidase E
References
Product Information
FormatSerum
PresentationSerum with 0.02% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Carboxypeptidase H Antibody, C-terminus is an antibody against Carboxypeptidase H for use in IP, WB & IC.
Key Applications
  • Immunoprecipitation
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry on AtT-20 cell line: 1:100-1:500.

Western blot: 1:500-1:2,000. Carboxypeptidase H precursor migrates at 53 kDa while active enzyme migrates at about 48 kDa.

Immunoprecipitation: 1:250-1:1,000

Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenSynthetic peptide corresponding to the C-terminus of Carboxypepdidase H conjugated to KLH.
EpitopeC-terminus
HostRabbit
SpecificityC-terminus of Carboxypepdidase H.
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
Gene Symbol
  • CPE
  • CPH
  • EC 3.4.17.10
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P16870 # Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.
COFACTOR: Binds 1 zinc ion per subunit (By similarity).
SIZE: 476 amino acids; 53151 Da
SUBCELLULAR LOCATION: Secreted. Note=Secretory granules of pancreatic islets, adrenal gland, pituitary and brain.
SIMILARITY: SwissProt: P16870 ## Belongs to the peptidase M14 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain frozen at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB5314 04053252624407

Documentation

Anti-Carboxypeptidase H Antibody, CT SDS

Title

Safety Data Sheet (SDS) 

Anti-Carboxypeptidase H Antibody, CT Certificates of Analysis

TitleLot Number
RABBIT ANTI-CARBOXYPEPTIDASE H POLYCLONAL ANTIBODY - 2161093 2161093
RABBIT ANTI-CARBOXYPEPTIDASE H POLYCLONAL ANTIBODY - 2396298 2396298
RABBIT ANTI-CARBOXYPEPTIDASE H - 3239839 3239839
RABBIT ANTI-CARBOXYPEPTIDASE H - 3998959 3998959
RABBIT ANTI-CARBOXYPEPTIDASE H POLYCLONAL ANTIBODY -2506275 2506275

Data Sheet

Title
RABBIT ANTI-CARBOXYPEPTIDASE H