116818 Sigma-AldrichAdenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt - Calbiochem
A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA).
More>> A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA). Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Sp-8-Br-cAMPS, Na
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Overview
Key Spec Table
| Empirical Formula |
|---|
| C₁₀H₁₀BrN₅O₅PS · Na |
| Description | |
|---|---|
| Overview | This product has been discontinued. A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA). Induces guanine nucleotide exchange factor activity of GEFI (also known as Epac) and GEFII towards Rap1 both in vivo and in vitro. Significantly more lipophilic and cell-permeable than Sp-cAMPS (Cat. No. 116815). Note: 5 µmol = 2.23 mg. |
| Catalogue Number | 116818 |
| Brand Family | Calbiochem® |
| Synonyms | Sp-8-Br-cAMPS, Na |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Declaration | Sold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI. |
| Form | Lyophilized |
| Hill Formula | C₁₀H₁₀BrN₅O₅PS · Na |
| Chemical formula | C₁₀H₁₀BrN₅O₅PS · Na |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | PKA |
| Purity | ≥99% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 116818 | 0 |