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504394 AIDA - CAS 168560-79-0 - Calbiochem

504394
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
168560-79-0C₁₁H₁₁NO₄

Products

Catalogue NumberPackaging Qty/Pack
5.04394.0001 Glass bottle 5 mg
Description
OverviewA relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo.
Catalogue Number504394
Brand Family Calbiochem®
Synonyms(RS)-1-Aminoindan-1,5-dicarboxylic acid, UPF 523
References
ReferencesPellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.
Product Information
CAS number168560-79-0
FormOff-white powder
Hill FormulaC₁₁H₁₁NO₄
Chemical formulaC₁₁H₁₁NO₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetmGlu1a
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +15°C to +30°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5.04394.0001 04055977264074

Documentation

References

Reference overview
Pellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.

Brochure

Title
Pathways and Biomarkers of Glutamatergic Synapse Flyer
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-June-2013 JSW
Synonyms(RS)-1-Aminoindan-1,5-dicarboxylic acid, UPF 523
DescriptionAA relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo.
FormOff-white powder
CAS number168560-79-0
Chemical formulaC₁₁H₁₁NO₄
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (2 mg/ml)
Storage Protect from light
+15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesPellicciari, R., et al. 1995. J. Med. Chem. 38, 3717.
Moroni, F., et al. 1997. J. Pharmacol. Exp. Ther. 281, 721.
Nielsen, K., et al. 1997. Eur. J. Pharmacol. 326, 105.
Christoffersen, G., et al. 1999, Neuropharmacology. 38, 817.