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504841 5,7-Dichlorokynurenic Acid, Sodium Salt - CAS 1184986-70-6 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic acid sodium salt, DCKA

Primary Target: NMDA receptors
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1184986-70-6C₁₀H₄Cl₂NNaO₃

Products

Catalogue NumberPackaging Qty/Pack
5.04841.0001 Glass bottle 10 mg
Description
OverviewA very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (Ki = 79 nM vs. [3H]-glycine).
Catalogue Number504841
Brand Family Calbiochem®
Synonyms5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic acid sodium salt, DCKA
References
ReferencesBaron, B., et al. 1991. Eur. J. Pharmacol. 206, 149.
Baron, B., et al. 1990. Mol. Pharmacol. 38, 554.
Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res. 18, 91.
Product Information
CAS number1184986-70-6
FormWhite solid
Hill FormulaC₁₀H₄Cl₂NNaO₃
Chemical formulaC₁₀H₄Cl₂NNaO₃
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNMDA receptors
Primary Target K<sub>i</sub>79 nM
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5.04841.0001 04055977243581

Documentation

5,7-Dichlorokynurenic Acid, Sodium Salt - CAS 1184986-70-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

5,7-Dichlorokynurenic Acid, Sodium Salt - CAS 1184986-70-6 - Calbiochem Certificates of Analysis

TitleLot Number
504841

References

Reference overview
Baron, B., et al. 1991. Eur. J. Pharmacol. 206, 149.
Baron, B., et al. 1990. Mol. Pharmacol. 38, 554.
Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res. 18, 91.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-November-2016 JSW
Synonyms5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic acid sodium salt, DCKA
DescriptionA very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (Ki = 79 nM vs. [3H]-glycine).
FormWhite solid
CAS number1184986-70-6
Chemical formulaC₁₀H₄Cl₂NNaO₃
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityH₂O (10 mM) or 1N NaOH (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesBaron, B., et al. 1991. Eur. J. Pharmacol. 206, 149.
Baron, B., et al. 1990. Mol. Pharmacol. 38, 554.
Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res. 18, 91.