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103132 1,4-Dioxane

1,4-Dioxane for liquid chromatography LiChrosolv®. CAS 123-91-1, pH 6 - 8 (500 g/l, H₂O, 20 °C).

1,4-Dioxane MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Glycolethylether, 1,4-Diethylene dioxide, 1,4-Dioxacyclohexane

CAS #: 123-91-1 EC Number: 204-661-8 Molar Mass: 88.11 g/mol Hill Formula: C₄H₈O₂
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar Mass
123-91-1204-661-8C₄H₈O₂88.11 g/mol

Products

Catalogue NumberPackaging Qty/Pack
1031321000 Glass bottle 1 l
1031322500 Glass bottle 2.5 l
Description
Catalogue Number103132
SynonymsGlycolethylether, 1,4-Diethylene dioxide, 1,4-Dioxacyclohexane
OverviewWith their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.
References
Product Information
CAS number123-91-1
EC index number603-024-00-5
EC number204-661-8
Hill FormulaC₄H₈O₂
Molar Mass88.11 g/mol
HS Code2932 99 99
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Application1,4-Dioxane for liquid chromatography LiChrosolv®. CAS 123-91-1, pH 6 - 8 (500 g/l, H₂O, 20 °C).
Biological Information
Physicochemical Information
Boiling point101.5 °C (1013 hPa)
Density1.034 g/cm3 (20 °C)
Explosion limit1.7 - 25.2 %(V)
Flash point11 °C
Ignition temperature300 °C
Melting Point11.8 °C
pH value6.0 - 8 (500 g/l, H₂O, 20 °C)
Vapor pressure36 hPa (20 °C)
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 5200 mg/kg
LD 50 dermalLD50 Rabbit 7600 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H225: Highly flammable liquid and vapour.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H350: May cause cancer.
EUH019: May form explosive peroxides.
EUH066: Repeated exposure may cause skin dryness or cracking.
Precautionary Statement(s)P202: Do not handle until all safety precautions have been read and understood.
P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233: Keep container tightly closed.
P240: Ground and bond container and receiving equipment.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal WordDanger
RTECSJG8225000
Storage class3 Flammable liquids
WGKWGK 3 highly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangerhighly flammable, irritant, carcinogenic
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 1165 , 3, II
Declaration (transport by air) IATA-DGRUN 1165 , 3, II
Declaration (transport by sea) IMDG-CodeUN 1165 , 3, II
Supplemental Information
Specifications
Purity (GC)≥ 99.8 %
Identity (IR)conforms
Evaporation residue≤ 2.0 mg/l
Water≤ 0.02 %
Acidity≤ 0.0002 meq/g
Alkalinity≤ 0.0002 meq/g
Transmission (at 245 nm)≥ 50 %
Transmission (at 270 nm)≥ 80 %
Transmission (from 300 nm)≥ 98 %
Filtered by 0.2 µm filter
Global Trade Item Number
Catalogue Number GTIN
1031321000 04022536040158
1031322500 04022536040165

Documentation

1,4-Dioxane SDS

Title

Safety Data Sheet (SDS) 

1,4-Dioxane Certificates of Analysis

Product Number PackagingSpecificationLot Number
1031321000 Glass bottlePDF Specification Document
1031322500 Glass bottlePDF Specification Document

Technical Info

Title
Pharmaceutical impurity profiling Application guide
Polar Hydrophilic Compounds in Pharmaceutical Analysis - SeQuant®ZIC®-HILIC HPLC for control of active ingredients, impurities, counterions and excipients.

Related Products & Applications

Accessories (Primary)

Catalogue Number Description
109996 Adapter S 40
963533 Safety carrier

Accessories (Secondary)

Catalogue Number Description
100801 Label set acc. GHS
103830 HPLC-bottle adapter with 3 tube connections ID 3.2 mm, solvents supply
103831 HPLC bottle adapter S40 with 3 tube connections and 1 connection for exhaust air filter, solvents disposal
103833 Exhaust air filter for HPLC bottle adapter S40, disposal
108801 Bottle key

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Categories

Reagents, Chemicals and Labware > Solvents > Solvents for Instrumental Organic Analysis > Solvents for Liquid Chromatography, LiChrosolv®
Analytics and Sample Preparation > Analytical Chromatography > Mobile Phases for Chromatography > Solvents for Liquid Chromatography, LiChrosolv®