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582235 Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem

The C-terminal binding portion of the heavy chain of tetanus toxin.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: TsTx-KαTTC

582235
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
582235-10UG Alu drum 10 μg
Description
OverviewThe C-terminal binding portion of the heavy chain of tetanus toxin. Useful for binding studies.
Caution: may contain trace amounts of intact toxin.
Catalogue Number582235
Brand Family Calbiochem®
SynonymsTsTx-KαTTC
References
ReferencesPoulain, B. 1994. Pathol. Biol. 42, 173.
Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.
Product Information
ATP CompetitiveN
FormLyophilized
FormulationLyophilized from 10 mM sodium phosphate buffer, pH 7.5.
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetUseful for binding studies
PuritySingle major band by SDS-PAGE
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 26/27/28

Very toxic by inhalation, in contact with skin and if swallowed.
S PhraseS: 45

In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Highly Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Once an aliquot has been thawed, do not refreeze. Aqueous stock solutions are stable for 7-10 days at 4°C.
Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
582235-10UG 04055977265682

Documentation

Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem Certificates of Analysis

TitleLot Number
582235

References

Reference overview
Poulain, B. 1994. Pathol. Biol. 42, 173.
Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-September-2007 RFH
SynonymsTsTx-KαTTC
DescriptionThe C-terminal binding portion of the chain of tetanus toxin. The intact toxin is known to block neurotransmitter release at inhibitory synapses in cultured spinal cord cells. Shows trans-synaptic retrograde transport in the central nervous system. Caution: may contain trace amounts of intact toxin. Follow the handling procedure described in the information that accompanies the product.
FormLyophilized
FormulationLyophilized from 10 mM sodium phosphate buffer, pH 7.5.
PuritySingle major band by SDS-PAGE
SolubilitySterile distilled H₂O
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Once an aliquot has been thawed, do not refreeze. Aqueous stock solutions are stable for 7-10 days at 4°C.
Toxicity Highly Toxic
ReferencesPoulain, B. 1994. Pathol. Biol. 42, 173.
Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.