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528175 Plasminogen, Human Plasma

528175
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
528175-120U Glass bottle 120 u
Description
OverviewNative plasminogen from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.
Catalogue Number528175
Brand Family Calbiochem®
SynonymsProfibrinolysin, Plasma Trypsinogen
References
ReferencesSun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.
Product Information
CAS number9001-91-6
Unit of DefinitionOne unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.
FormLyophilized
FormulationLyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥120 units/mg protein.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
528175-120U 04055977196436

Documentation

Plasminogen, Human Plasma SDS

Title

Safety Data Sheet (SDS) 

Plasminogen, Human Plasma Certificates of Analysis

TitleLot Number
528175

References

Reference overview
Sun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-May-2008 RFH
SynonymsProfibrinolysin, Plasma Trypsinogen
DescriptionNative plasminogen from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. Plasminogen is converted to the active protease by cleavage at Arg560.
FormLyophilized
FormulationLyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number9001-91-6
Purity≥95% by SDS-PAGE
Specific activity≥120 units/mg protein.
Unit definitionOne unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.
SolubilityH₂O
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
Toxicity Irritant
Merck USA index14, 7521
ReferencesSun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.