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200488 InSolution™Bestatin, Hydrochloride - Calbiochem

200488
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₆H₂₄N₂O₄ • HCl

Products

Catalogue NumberPackaging Qty/Pack
200488-10MG Glass bottle 10 mg
Description
OverviewA metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available.
Catalogue Number200488
Brand Family Calbiochem®
Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl
References
ReferencesMerck Index: 14, 9842.
Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
Taylor, A., et al. 1993. Biochemistry 32, 784.
Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
Product Information
FormLiquid
FormulationSupplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O.
Hill FormulaC₁₆H₂₄N₂O₄ • HCl
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMetalloproteases
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
200488-10MG 04055977221510

Documentation

InSolution™Bestatin, Hydrochloride - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

InSolution™Bestatin, Hydrochloride - Calbiochem Certificates of Analysis

TitleLot Number
200488

References

Reference overview
Merck Index: 14, 9842.
Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
Taylor, A., et al. 1993. Biochemistry 32, 784.
Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision21-September-2012 JSW
Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl
DescriptionA metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available.
FormLiquid
FormulationSupplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O.
Intert gas (Yes/No) Packaged under inert gas
Structure formulaStructure formula
Purity≥98% by HPLC
Storage Protect from light
Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesMerck Index: 14, 9842.
Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
Taylor, A., et al. 1993. Biochemistry 32, 784.
Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.