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GF440 HumanKine® TGF beta 2, Human Recombinant Xeno-Free

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P61812
GF440
5 µg  
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Overview

Replacement Information

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Key Spec Table

SourcePurity
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
Description
Catalogue NumberGF440
Trade Name
  • HumanKine®
DescriptionHumanKine® TGF beta 2, Human Recombinant Xeno-Free
Alternate Names
  • TGFb2
  • TGFbII
  • TGFB
  • Transforming Growth Factor-β2
Background InformationTransforming Growth Factor- beta2 (TGFb2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. TGfb2 regulates proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers.
References
Product Information
Formulation
PresentationProduct is presented in 50mM NaOAc pH 4.5 and filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ300
Applications
Biological Information
PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by the dose dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2). ED50 is typically 0.1-0.5 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Packaging Information
Material Size5 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF440 04053252906077

Documentation

HumanKine® TGF beta 2, Human Recombinant Xeno-Free Certificates of Analysis

TitleLot Number
HumanKine#174; TGF beta 2, Human Recombinant Xeno-Free - QVP1303163 QVP1303163
HumanKine® TGF beta 2, -VP1603318 VP1603318
HumanKine® TGF beta 2, -VP1605074 VP1605074
HumanKine® TGF beta 2, Human Recombinant Xeno-Free - VP1908142 VP1908142
HumanKine® TGF beta 2, Human Recombinant Xeno-Free -VP1604182 VP1604182
HumanKine® TGF beta 2, Human Recombinant Xeno-Free Recombinant Protein VP1710193

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Categories

Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors