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345832 Galectin-3C, Human, Recombinant, E. coli

345832
Purchase on Sigma-Aldrich

Overview

Products

Catalogue NumberPackaging Qty/Pack
345832-100UG Plastic ampoule 100 μg
Description
OverviewRecombinant, human galectin-3 expressed in E. coli and subsequently cleaved with Clostridium histolyticum collagenase type VII to yield galectin-3C. The resulting galectin-3C is purified by affinity chromatography. Galectin-3C is a truncated form of galectin-3 that contains the carbohydrate binding domain but lacks the 107 amino acids at the N-terminus of galectin-3. It is suggested to play a key role in autoimmune diseases, allergic reactions, inflammation, tumor cell metastasis, atherosclerosis, and diabetes.
Catalogue Number345832
Brand Family Calbiochem®
References
ReferencesHoyer K.K., et al. 2004. Am. J. Pathol. 164, 893.
John C.M., et al. 2003. Clin. Cancer Res. 9, 2374.
Iurisci, I., et al. 2000. Clin Cancer Res 6, 1389.
Van Den Brule, F. A., et al. 2000. Int. J. Cancer 89, 361.
Inohara, H. 1999. Cancer 85, 2475.
Nakamura, M., et al. 1999. Int. J. Oncol. 15, 143.
Idikio, H., et al. 1998. Int. J. Oncol. 12, 1287.
Ochieng, J., et al. 1998. Biochim. Biophys. Acta. 1379 97.
Castronovo, V., et al. 1996. J. Pathol. 179, 43.
Liu, F.T., et al. 1996. Biochemistry 35 6073.
Schoeppner, H. L., et al. 1995. Cancer 75, 2818.
Massa, S.M., et al. 1993. Biochemistry 32, 260.
Oda, Y., et al. 1991. Gene 99, 279.
Product Information
FormLyophilized
FormulationLyophilized from deionized water, 2µg lactose/µg lectin.
Quality LevelMQ100
Biological Information
Purity≥95% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: ≤ 1 EU/µg protein
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions (in the presence of a molar excess of lactose) are stable for up to 4 months at -20°C. For use in carbohydrate binding assays the solution should be dialyzed to remove the lactose stabilizer.
Global Trade Item Number
Catalogue Number GTIN
345832-100UG 04055977214352