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12-330 Casein Kinase 2 Substrate Peptide

Casein Kinase 2 Substrate Peptide primarily used in Kinase Assays.

Casein Kinase 2 Substrate Peptide MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
12-330
1 µmol  
Purchase on Sigma-Aldrich

Overview

Description
Catalogue Number12-330
Brand Family Upstate
Trade Name
  • Upstate
DescriptionCasein Kinase 2 Substrate Peptide
Product Information
Presentation20 mM MOPS, pH 7.2; 25 mM b-glycerol phosphate; 5 mM EGTA; 1 mM sodium orthovanadate; 1 mM dithiothreitol
Quality LevelMQ300
Applications
ApplicationCasein Kinase 2 Substrate Peptide primarily used in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Entrez Gene Number
Entrez Gene SummaryThis gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
Gene Symbol
  • CSNK2B
  • Phosvitin
  • CK2B
  • CSK2B
  • MGC138224
  • MGC138222
  • CK2N
  • G5a
  • phosvitin
  • G5A
Protein TargetCK2
Target Sub-FamilyCMGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P67870 # Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
SIZE: 215 amino acids; 24942 Da
SUBUNIT: Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
PTM: Phosphorylated by alpha subunit.
SIMILARITY: SwissProt: P67870 ## Belongs to the casein kinase 2 subunit beta family.
Product Usage Statements
Quality AssuranceRoutinely evaluated as a substrate in a kinase assay.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of the product, centrifuge the original vial prior to removing the cap.
Packaging Information
Material Size1 µmol
Global Trade Item Number
Catalogue Number GTIN
12-330 04053252512360