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01-195 CNTF, recombinant

CNTF, recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Cell Culture UniProt Number: P26441 Entrez Gene Number: NM_000614.2
01-195
25 µg  
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Overview

Replacement Information
Description
Catalogue Number01-195
Brand Family Upstate
Trade Name
  • Upstate
DescriptionCNTF, recombinant
References
Product Information
PresentationLyophilized from 5mM sodium acetate, pH 6.5.
Quality LevelMQ100
Applications
Key Applications
  • Cell Culture
Biological Information
SourceRecombinant rat Ciliary Neurotrophic Factor expressed in E. coli
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor.
Gene Symbol
  • CNTF
  • HCNTF
Purification MethodSterilized through a 0.2 micron membrane filter
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P26441 # CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
SIZE: 200 amino acids; 22931 Da
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Nervous system.
SIMILARITY: SwissProt: P26441 ## Belongs to the CNTF family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated in a biological activity assay.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size25 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
01-195 04053252331909

Documentation

CNTF, recombinant SDS

Title

Safety Data Sheet (SDS) 

CNTF, recombinant Certificates of Analysis

TitleLot Number
CNTF (recombinant protein expressed in E. coli) - 2115523 2115523
CNTF (recombinant protein expressed in E. coli) - 2138536 2138536
CNTF (recombinant protein expressed in E. coli) 2459019
CNTF (recombinant protein expressed in E. coli) - 1982678 1982678
CNTF (recombinant protein expressed in E. coli) - 2219254 2219254
CNTF (recombinant protein expressed in E. coli) - 2318069 2318069
CNTF (recombinant protein expressed in E. coli) - 3427185 3427185
CNTF (recombinant protein expressed in E. coli) - 3723408 3723408
CNTF (recombinant protein expressed in E. coli) - 3940595 3940595
CNTF (recombinant protein expressed in E. coli) - 4164918 4164918
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