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178223 Antipain, Dihydrochloride - CAS 37682-72-7 - Calbiochem

178223
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Overview

Key Spec Table

CAS #Empirical Formula
37682-72-7C₂₇H₄₄N₁₀O₆ · 2HCl

Products

Catalogue NumberPackaging Qty/Pack
178223-10MG Plastic ampoule 10 mg
Description
OverviewPeptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain and some cysteine proteases (IC50 = 300 µM).
Effective concentration: 1-100 µM.
Catalogue Number178223
Brand Family Calbiochem®
References
ReferencesLyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
Ichikawa, S., et al. 1985. J. Reprod. Fertil. 73, 385
Umezawa, H. 1976. Methods Enzymol. 55, 678.
Suda, H., et al. 1972. J. Antibiot. (Tokyo) 25, 263.
Product Information
CAS number37682-72-7
ATP CompetitiveN
FormWhite powder
Hill FormulaC₂₇H₄₄N₁₀O₆ · 2HCl
Chemical formulaC₂₇H₄₄N₁₀O₆ · 2HCl
Hygroscopic Hygroscopic
ReversibleY
Quality LevelMQ100
Biological Information
Primary Targettrypsin-like serine proteases, papain, and some cysteine proteases
Primary Target IC<sub>50</sub>300 µM against trypsin-like serine proteases, papain and some cysteine proteases; Effective concentration: 1-100 µM
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Safety Information according to GHS
RTECSYV9350800
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
Global Trade Item Number
Catalogue Number GTIN
178223-10MG 04055977223118