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ABC98 Anti-PRUNE Antibody

ABC98
100 µL  
Purchase on Sigma-Aldrich

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Overview

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC98
DescriptionAnti-PRUNE Antibody
Alternate Names
  • Protein prune homolog
  • hPrune
  • Drosophila-related expressed sequence 17
  • DRES-17
  • DRES17
  • HTcD37
Background InformationProtein prune homolog, otherwise known as PRUNE or Drosophila-related expressed sequence 17, is a phosphodiesterase enzyme belonging to the PPase class C family. PRUNE targets cAMP and cGMP second messengers and plays a role in cell proliferation and motility. It is overexpressed in various sarcomas, including leiomyosarcomas, malignant fibrous histiocytomas, and malignant liposarcomas.
Product Information
FormatAffinity Purified
Control
  • HeLa S3 cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect PRUNE using this Anti-PRUNE Antibody validated for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human PRUNE.

HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PRUNE
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~57 kDa observed
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in HeLa S3 cell lysate.

Western Blot Analysis: A 1:5,000 dilution of this antibody detected PRUNE in 10 µg of HeLa S3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Global Trade Item Number
Catalogue Number GTIN
ABC98 04053252599989