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MABN314 Anti-Gamma-synuclein (SNCG), clone 3D2.1 Antibody

MABN314
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN314
DescriptionAnti-Gamma-synuclein (SNCG), clone 3D2.1 Antibody
Alternate Names
  • Gamma-synuclein
  • Breast cancer-specific gene 1 protein
  • Persyn
  • Synoretin
  • SR
Background InformationGamma-synuclein is one four proteins in the synuclein family, Gamma-synuclein appears to play a role in neurofilament network integrity and interaction. Gamma synuclein is important for axonal architecture and maintenance and the protein interacts with both the MAPK and ELK-1 signaling networks. Gamma synuclein is a cytoplasmically associated protein that is also strongly associated with cytoskeletal elements. During cell division, gamma synuclein is associated with the poles of the spindle and interruption causes defects in cytokinesis. Gamma synuclein is highly expressed in the brain but can also be found expressed in the heart, skeletal muscle, colon, and gonads. Gamma synuclein is also expressed in many invasive cancers.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Gamma-synuclein (SNCG), clone 3D2.1 Antibody is validated for use in Western Blotting for the detection of Gamma-synuclein (SNCG).
Key Applications
  • Western Blotting
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Gamma-synuclein (SNCG).
Clone3D2.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • SNCG
  • BCSG1
  • PERSYN
  • PRSN
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~15 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Gamma-synuclein (SNCG) in 10 µg of human cortex tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN314 04053252986536