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505986 SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531

Primary Target: GABAA
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
104104-50-9C₁₅H₁₇N₃O₃•HBr

Products

Catalogue NumberPackaging Qty/Pack
5059860001 Glass bottle 10 mg
Description
OverviewA selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 µM). Also shown to block glycine receptors, but with low affinity (Kb = 190 µM).
Catalogue Number505986
Brand Family Calbiochem®
SynonymsGABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
References
ReferencesMuroi, Y., et al. 2009. Biophys. J. 96, 499.
Beato, M., et al. 2007. J. Physiol. 580, 171.
Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.
Product Information
CAS number104104-50-9
FormWhite solid
Hill FormulaC₁₅H₁₇N₃O₃•HBr
Chemical formulaC₁₅H₁₇N₃O₃•HBr
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetGABAA
Primary Target IC<sub>50</sub>440 nM
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5059860001 04055977262582

Documentation

SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Muroi, Y., et al. 2009. Biophys. J. 96, 499.
Beato, M., et al. 2007. J. Physiol. 580, 171.
Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-September-2013 JSW
SynonymsGABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
DescriptionA selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 mM). Also shown to block glycine receptors, but with low affinity (Kb = 190 mM).
FormWhite solid
CAS number104104-50-9
Chemical formulaC₁₅H₁₇N₃O₃•HBr
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (25 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesMuroi, Y., et al. 2009. Biophys. J. 96, 499.
Beato, M., et al. 2007. J. Physiol. 580, 171.
Uchida, I., et al. 1996. Eur. J. Pharmacol. 307, 89.