Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

539165 Proteasome Inhibitor Set II - Calbiochem

The Proteasome Inhibitor Set II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Proteasome Inhibitor Set II - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: calpain 1, calpain 2
539165
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
539165-1SET Glass bottle 1 set
Description
OverviewContains 5 mg of ALLN (Cat. No. 208719), 100 μg each of Epoxomicin (Cat. No. 324800), and clasto-Lactacystin β-Lactone (Cat. No. 426102). Supplied with a data sheet.
Catalogue Number539165
Brand Family Calbiochem®
References
Product Information
FormSolid
Quality LevelMQ100
Applications
Biological Information
Primary Targetcalpain 1, calpain 2
Secondary targetcathepsin B, cathepsin L
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
539165-1SET 07790788051303

Documentation

Proteasome Inhibitor Set II - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Proteasome Inhibitor Set II - Calbiochem Certificates of Analysis

TitleLot Number
539165

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-September-2008 RFH
DescriptionProteasomes are large multi-subunit protease complexes, which selectively degrade intracellular proteins. A protein marked for degradation is attached to multiple molecules of ubiquitin, a 76-amino acid protein, which escorts it for rapid hydrolysis, by the 26S proteasome. The proteolytic core of this complex consists of the 20S proteasome, which contains multiple peptidase activities and has a molecular mass of ~700 kDa. Recently several potent, cell-permeable proteasome inhibitors have been developed.

The Calbiochem® brand offers a set that includes 3 proteasome inhibitors with varying inhibtory effects.

The table below outlines some of the physical and biological properties of these compounds.
FormSolid
Intert gas (Yes/No) Packaged under inert gas
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Toxicity Standard Handling