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444235 MMP-13 Substrate, Fluorogenic - Calbiochem

444235
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Overview

Products

Catalogue NumberPackaging Qty/Pack
444235-1MG Plastic ampoule 1 mg
Description
OverviewA quenched fluorescence substrate for MMP-13 (collagenase-3; kcat/Km = 1.09 x 106 M-1s-1). Less efficient as a substrate for MMP-1 (fibroblast collagenase) or MMP-8 (neutrophil collagenase).
Catalogue Number444235
Brand Family Calbiochem®
SynonymsCollagenase-3 Substrate, Fluorogenic
References
ReferencesKnauper, V., et al. 1996. J. Biol. Chem. 271, 1544.
Product Information
ATP CompetitiveN
FormYellow lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₅₁H₆₅N₁₃O₁₅
Chemical formulaC₅₁H₆₅N₁₃O₁₅
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetA quenched fluorescence substrate for MMP-13 (collagenase-3)
Primary Target IC<sub>50</sub>kcat/Km = 1.09 x 106 M⁻¹ sec⁻¹ for MMP-13 (collagenase-3)
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide SequenceMCA-Pro-Cha-Gly-Nva-His-Ala-Dpa-NH₂ [Cha = L-cyclohexylalanine; Dpa = 3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl; Nva = L-norvaline]
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
444235-1MG 04055977186420