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444221 MMP-1/MMP-9 Substrate, Fluorogenic - Calbiochem

An excellent quenched fluorescence substrate for MMP-1 and MMP-9.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
444221
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
444221-1MG Plastic ampoule 1 mg
Description
OverviewAn excellent quenched fluorescence substrate for MMP-1 and MMP-9. Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values.
Catalogue Number444221
Brand Family Calbiochem®
References
ReferencesBickett, D.M., et al. 1993. Anal. Biochem. 212, 58.
Product Information
ATP CompetitiveN
FormYellow solid
Hill FormulaC₄₉H₆₈N₁₄O₁₂S
Chemical formulaC₄₉H₆₈N₁₄O₁₂S
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-1, MMP-9
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide Sequence{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
444221-1MG 04055977205244

Documentation

MMP-1/MMP-9 Substrate, Fluorogenic - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

MMP-1/MMP-9 Substrate, Fluorogenic - Calbiochem Certificates of Analysis

TitleLot Number
444221

References

Reference overview
Bickett, D.M., et al. 1993. Anal. Biochem. 212, 58.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2007 JSW
DescriptionAn excellent quenched fluorescence substrate for MMP-1 and MMP-9 (excitation maximum: 365 nm; emission maximum: 450 nm). Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values. Excitation max: ~365 nm; emission max: ~450 nm.
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₄₉H₆₈N₁₄O₁₂S
Peptide Sequence{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]
Purity≥95% by HPLC
SolubilityH₂O (1 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Toxicity Standard Handling
ReferencesBickett, D.M., et al. 1993. Anal. Biochem. 212, 58.