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428020 Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem

Latrunculin B, CAS 76343-94-7, is a unique marine toxin that inhibits actin polymerization and disrupts microfilament organization. It is 10 to 100-fold more potent than cytochalasins.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Actin polymerization
428020
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
76343-94-7C₂₀H₂₉NO₅S

Products

Catalogue NumberPackaging Qty/Pack
428020-1MG Plastic ampoule 1 mg
428020-5MG Plastic ampoule 5 mg
Description
OverviewA structurally unique marine toxin. Inhibits actin polymerization in vitro and disrupts microfilament organization as well as microfilament-mediated processes; 10 to 100-fold more potent than cytochalasins.
Catalogue Number428020
Brand Family Calbiochem®
References
ReferencesSpector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
de Oliveira, C.A., and Mantovani, B. 1988. Life Sci. 43, 1825.
Coue, M., et al. 1987. FEBS Lett. 213, 316.
Spector, I., et al. 1983. Science 219, 493.
Product Information
CAS number76343-94-7
ATP CompetitiveN
FormOff-white to yellow solid
Hill FormulaC₂₀H₂₉NO₅S
Chemical formulaC₂₀H₂₉NO₅S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetActin polymerization
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
428020-1MG 04055977210453
428020-5MG 04055977210460

Documentation

Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem Certificates of Analysis

TitleLot Number
428020

References

Reference overview
Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
de Oliveira, C.A., and Mantovani, B. 1988. Life Sci. 43, 1825.
Coue, M., et al. 1987. FEBS Lett. 213, 316.
Spector, I., et al. 1983. Science 219, 493.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-January-2011 JSW
DescriptionA structurally unique marine toxin. Inhibits actin polymerization in vitro and disrupts microfilament organization as well as microfilament-mediated processes. 10 to 100-fold more potent than cytochalasins.
FormOff-white to yellow solid
CAS number76343-94-7
Chemical formulaC₂₀H₂₉NO₅S
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml), Methanol (50 mg/ml),or Ethanol (25 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Harmful
Merck USA index14, 5378
ReferencesSpector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
de Oliveira, C.A., and Mantovani, B. 1988. Life Sci. 43, 1825.
Coue, M., et al. 1987. FEBS Lett. 213, 316.
Spector, I., et al. 1983. Science 219, 493.