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420305 K-252c - CAS 85753-43-1 - Calbiochem

A cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (IC₅₀ = 2.45 µM) and protein kinase A (IC₅₀ = 25.7 µM).

K-252c - CAS 85753-43-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: PKC
420305
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
85753-43-1C₂₀H₁₃N₃O

Products

Catalogue NumberPackaging Qty/Pack
420305-1MG Plastic ampoule 1 mg
Description
OverviewA cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (IC50 = 2.45 µM) and protein kinase A (IC50 = 25.7 µM).
Catalogue Number420305
Brand Family Calbiochem®
References
ReferencesFabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.
Product Information
CAS number85753-43-1
ATP CompetitiveY
FormOff-white solid
Hill FormulaC₂₀H₁₃N₃O
Chemical formulaC₂₀H₁₃N₃O
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPKC
Primary Target IC<sub>50</sub>2.45 µM against protein kinase C
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
420305-1MG 04055977210927

Documentation

K-252c - CAS 85753-43-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

K-252c - CAS 85753-43-1 - Calbiochem Certificates of Analysis

TitleLot Number
420305

References

Reference overview
Fabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-April-2011 RFH
DescriptionA cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (IC50 = 25.7 µM) and protein kinase C (IC50 = 2.45 µM).
FormOff-white solid
CAS number85753-43-1
Chemical formulaC₂₀H₁₃N₃O
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml) or Methanol
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesFabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.