324674 Sigma-AldrichEGFR Inhibitor - CAS 879127-07-8 - Calbiochem
The EGFR Inhibitor, also referenced under CAS 879127-07-8, controls the biological activity of EGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica
More>> The EGFR Inhibitor, also referenced under CAS 879127-07-8, controls the biological activity of EGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Cyclopropanecarboxylic acid-(3-(6-(3-trifluoromethyl-phenylamino)-pyrimidin-4-ylamino)-phenyl)-amide
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Overview
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 879127-07-8 | C₂₁H₁₈F₃N₅O |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 324674-1MG | Plastic ampoule | 1 mg |
| References | |
|---|---|
| References | Zhang, Q., et al. 2006. J. Am. Chem. Soc. 128, 2182 |
| Product Information | |
|---|---|
| CAS number | 879127-07-8 |
| ATP Competitive | Y |
| Form | Off-white solid |
| Hill Formula | C₂₁H₁₈F₃N₅O |
| Chemical formula | C₂₁H₁₈F₃N₅O |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | EGFR |
| Primary Target IC<sub>50</sub> | 21 nM, 63 nM, and 4 nM for EGFRwt, EGFRL858R and EGFRL861Q, respectively |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 324674-1MG | 04055977196764 |