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AG235 Dopamine D4, Mouse, Ms, Control Peptide for AB1787P

AG235
100 µg  
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Overview

Description
Catalogue NumberAG235
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionDopamine D4, Mouse, Ms, Control Peptide for AB1787P
Overview10 amino acid peptide sequence from the mouse D4 receptor within the 3rd extracellular domain.
Product Information
PresentationLiquid in PBS, pH 7.4 containing 0.02% sodium merthiolate.
Quality LevelMQ100
Applications
Key Applications
  • Cell Function Assay
Application NotesFor use in blocking the reactivity of AB1787P.

Optimal working dilution must be determined by the end user.
Biological Information
Concentration1.0 mg/mL
Entrez Gene Number
Entrez Gene SummaryThis gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Gene Symbol
  • DRD4
  • D
  • D4DR
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P21917 # This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
SIZE: 467 amino acids; 48361 Da
SUBUNIT: Interacts with CLIC6 (By similarity) and GPRASP1.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P21917 ## Belongs to the G-protein coupled receptor 1 family.
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µg
Global Trade Item Number
Catalogue Number GTIN
AG235 04053252274664