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513100 DL-threo-PDMP, Hydrochloride - CAS 80938-69-8 - Calbiochem

PDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl

Primary Target: glycolipid synthesis in cultured NIH/3T3 cells
513100
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
80938-69-8C₂₃H₃₈N₂O₃ · HCl

Products

Catalogue NumberPackaging Qty/Pack
513100-50MG Plastic ampoule 50 mg
Description
OverviewPDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured NIH/3T3 cells.
Catalogue Number513100
Brand Family Calbiochem®
Synonyms1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl
References
ReferencesRani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
Rosenwald, A.G. 1992. Biochemistry 31, 3581.
Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.
Product Information
CAS number80938-69-8
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₃H₃₈N₂O₃ · HCl
Chemical formulaC₂₃H₃₈N₂O₃ · HCl
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetglycolipid synthesis in cultured NIH/3T3 cells
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
513100-50MG 04055977198683

Documentation

DL-threo-PDMP, Hydrochloride - CAS 80938-69-8 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

DL-threo-PDMP, Hydrochloride - CAS 80938-69-8 - Calbiochem Certificates of Analysis

TitleLot Number
513100

References

Reference overview
Rani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
Rosenwald, A.G. 1992. Biochemistry 31, 3581.
Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-October-2023 JSW
Synonyms1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl
DescriptionPDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and is a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured 3T3 cells.
FormWhite solid
CAS number80938-69-8
Chemical formulaC₂₃H₃₈N₂O₃ · HCl
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO, methanol, or ethanol
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
Toxicity Irritant
ReferencesRani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
Rosenwald, A.G. 1992. Biochemistry 31, 3581.
Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.