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508015
Sigma-AldrichCTOP - CAS 103429-31-8 - Calbiochem
A potent antagonist highly selective for µ opioid receptor (Ki = 0.96 nM for µ receptor and > 10,000 nM for δ receptors). Often used for studying the functional roles of µ opioid receptors in both central and peripheral nervous systems.
Catalogue Number
508015
Brand Family
Calbiochem®
Synonyms
µ Opioid Receptor Antagonist, CTOP
References
References
Feng, Y., et al. 2012. Curr Drug Targets.13, 230. Hawkins, N., et al. 1989. J. Pharmacol. Exp. Ther.248, 73. Gulya, K., et al. 1988. Eur. J. Pharmacol.150, 355.
CTOP - CAS 103429-31-8 - Calbiochem Certificates of Analysis
Title
Lot Number
508015
References
Reference overview
Feng, Y., et al. 2012. Curr Drug Targets.13, 230. Hawkins, N., et al. 1989. J. Pharmacol. Exp. Ther.248, 73. Gulya, K., et al. 1988. Eur. J. Pharmacol.150, 355.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
13-September-2024 JSW
Synonyms
µ Opioid Receptor Antagonist, CTOP
Description
A potent antagonist highly selective for µ opioid receptor (Ki = 0.96 nM for µ receptor and > 10,000 nM for δ receptors). Often used for studying the functional roles of µ opioid receptors in both central and peripheral nervous systems.
Form
White solid
Formulation
Supplied as trifluoracetate salt
CAS number
103429-31-8
Chemical formula
C₅₀H₆₇N₁₁O₁₁S₂
Peptide Sequence
D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (Orn: ornithine; Pen: penicillamine; SS bond: 2-7)
Structure formula
Purity
≥95% by HPLC
Solubility
H₂O
Storage
Protect from light -20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Feng, Y., et al. 2012. Curr Drug Targets.13, 230. Hawkins, N., et al. 1989. J. Pharmacol. Exp. Ther.248, 73. Gulya, K., et al. 1988. Eur. J. Pharmacol.150, 355.