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MABN369 Anti-Neuroglobin Antibody, clone 6G1.1

MABN369
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN369
DescriptionAnti-Neuroglobin Antibody, clone 6G1.1
Alternate Names
  • Neuroglobin
Background InformationNeuroglobin protein encoded by the gene NGB, is involved in oxygen transport in the brain. Neuroglobin is also important for neuroprotection during oxidative stress. Additionally, Neuroglobin has anti-apoptotic activity by reseting the mitochondrial membrane tigger level for cytochrome C release and the commitment to apoptosis. Neuroglobin is localized to the perikaryon, cytoplasm, and mitochondrion. Neuroglobin is predominantly expressed in the brain with strongest expression in the frontal lobe and the subthalamic nucleus and thalamus.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Neuroglobin using this mouse monoclonal antibody, Anti-Neuroglobin Antibody, clone 6G1.1 validated for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroglobin in human thalamus and human frontal lobe tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the N-terminus of human Neuroglobin.
EpitopeN-terminus
Clone6G1.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • NGB
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~17 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroglobin in 10 µg of human cortex tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN369 04053252930904

Documentation

Anti-Neuroglobin Antibody, clone 6G1.1 SDS

Title

Safety Data Sheet (SDS) 

Anti-Neuroglobin Antibody, clone 6G1.1 Certificates of Analysis

TitleLot Number
Anti-Neuroglobin, clone 6G1.1 - 3211297 3211297
Anti-Neuroglobin, clone 6G1.1 - 3328970 3328970
Anti-Neuroglobin, clone 6G1.1 - 3420903 3420903
Anti-Neuroglobin, clone 6G1.1 - 3593175 3593175
Anti-Neuroglobin, clone 6G1.1 - Q2290325 Q2290325
Anti-Neuroglobin, clone 6G1.1 -2834507 2834507
Anti-Neuroglobin, clone 6G1.1 Monoclonal Antibody 2967198
Anti-Neuroglobin, clone 6G1.1 Monoclonal Antibody 3059619
Anti-Neuroglobin, clone 6G1.1 Monoclonal Antibody 2930029