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MABF94 Anti-BDCA-2 Antibody, clone 10E6.1

Detect BDCA-2 using this Anti-BDCA-2 Antibody, clone 10E6.1 validated for use in Western Blotting & IHC.

Anti-BDCA-2 Antibody, clone 10E6.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: CLEC4C, BDCA2, CLECSF11, CLECSF7, DLEC, HECL UniProt Number: Q8WTT0
MABF94
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABF94
DescriptionAnti-BDCA-2 Antibody, clone 10E6.1
Alternate Names
  • C-type lectin domain family 4 member C
  • Blood dendritic cell antigen 2
  • BDCA-2
  • C-type lectin superfamily member 7
  • Dendritic lectin
  • CD303
Background InformationBlood dendritic cell antigen 2 (BDCA-2;CD303) is a type II C-type lectin that is expressed on plasmacytoid dendritic cells (PDC), a subset of immature dendritic cells found in lymphoid and nonlymphoid tissues. BDCA-2 is critically involved in both adaptive and innate immune responses. It is involved in the recognition and internalization of pathogens, but inhibits TLR6 signaling and INF-1 production, in PDC cells, possibly through signaling of the BCR-like signalosome. PDC signaling has been linked to multiple inflammatory diseases such as granulomatous lymphadenitis.
References
Product Information
FormatPurified
HS Code3002 15 90
Control
  • Recombinant BDCA-2 protein
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect BDCA-2 using this Anti-BDCA-2 Antibody, clone 10E6.1 validated for use in Western Blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected BDCA-2 in human tonsil tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human BDCA-2.
Clone10E6.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • CLEC4C
  • BDCA2
  • CLECSF11
  • CLECSF7
  • DLEC
  • HECL
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~33 kDa observed. Uncharacterized bands appear at ~25 and ~31 kDa in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in recombinant BDCA-2 protein.

Western Blot Analysis: 1 µg/mL of this antibody detected BDCA-2 on 10 µg of recombinant BDCA-2 protein.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABF94 04053252691959

Documentation

Anti-BDCA-2 Antibody, clone 10E6.1 SDS

Title

Safety Data Sheet (SDS) 

Anti-BDCA-2 Antibody, clone 10E6.1 Certificates of Analysis

TitleLot Number
Anti-BDCA-2, clone 10E6.1 2480956
Anti-BDCA-2, clone 10E6.1 - 2360028 2360028
Anti-BDCA-2, clone 10E6.1 - 2463175 2463175
Anti-BDCA-2, clone 10E6.1 - 2172778 2172778
Anti-BDCA-2, clone 10E6.1 - 2201526 2201526
Anti-BDCA-2, clone 10E6.1 - 2239643 2239643
Anti-BDCA-2, clone 10E6.1 - 3313744 3313744
Anti-BDCA-2, clone 10E6.1 - 3508390 3508390
Anti-BDCA-2, clone 10E6.1 - 3698182 3698182
Anti-BDCA-2, clone 10E6.1 - 3745548 3745548
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