532996 Sigma-AldrichAndrogen Receptor DBD Inhibitor, VPC-14449 - CAS 1621375-32-3 - Calbiochem
VPC-14449, is a cell-permeable compound that selectively binds to the DNA-binding domain of androgen receptor (AR) and blocks its activity (IC₅₀ = 340 nM in PC3 cells).
More>> VPC-14449, is a cell-permeable compound that selectively binds to the DNA-binding domain of androgen receptor (AR) and blocks its activity (IC₅₀ = 340 nM in PC3 cells). Less<<Synonyms: AR-DBD Inhibitor, VPC-14449, VPC14449, VPC 14449
Recommended Products
Overview
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Key Spec Table
CAS # | Empirical Formula |
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1621375-32-3 | C₁₀H₁₀Br₂N₄OS |
Products
Catalogue Number | Packaging | Qty/Pack | |
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5329960001 | Glass bottle | 10 mg |
References | |
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References | Dalal, K., et al. 2014. J. Biol. Chem. 289, 26417. |
Product Information | |
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CAS number | 1621375-32-3 |
Form | Off-white solid |
Hill Formula | C₁₀H₁₀Br₂N₄OS |
Chemical formula | C₁₀H₁₀Br₂N₄OS |
Reversible | Y |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | Androgen Receptor |
Primary Target IC<sub>50</sub> | 947 nM |
Purity | ≥98% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Transport Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalogue Number | GTIN |
5329960001 | 04055977282009 |
Documentation
Androgen Receptor DBD Inhibitor, VPC-14449 - CAS 1621375-32-3 - Calbiochem SDS
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Androgen Receptor DBD Inhibitor, VPC-14449 - CAS 1621375-32-3 - Calbiochem Certificates of Analysis
Title | Lot Number |
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532996 |
References
Reference overview |
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Dalal, K., et al. 2014. J. Biol. Chem. 289, 26417. |