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568500 SQ 22536 - CAS 17318-31-9 - Calbiochem

Cell-permeable adenylate cyclase inhibitor.

SQ 22536 - CAS 17318-31-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 9-(Tetrahydro-2ʹ-furyl)adenine

Primary Target: adenylate cyclase
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568500
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
17318-31-9C₉H₁₁N₅O

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      Description
      OverviewCell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC50 = 200 µM). Reduces PGE2-induced inhibition of O2·– production.
      Catalogue Number568500
      Brand Family Calbiochem®
      Synonyms9-(Tetrahydro-2ʹ-furyl)adenine
      References
      ReferencesTalpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
      Tamaoki, J., et al. 1993. Prostaglandins 45, 363.
      Fabbri, E., et al. 1991. J. Enzyme Inhib. 5, 87.
      Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.
      Product Information
      CAS number17318-31-9
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₉H₁₁N₅O
      Chemical formulaC₉H₁₁N₅O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetadenylate cyclase
      Primary Target IC<sub>50</sub>200 µM against adenylate cyclase
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      568500-5MG 04055977190397

      Documentation

      SQ 22536 - CAS 17318-31-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      SQ 22536 - CAS 17318-31-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      568500

      References

      Reference overview
      Talpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
      Tamaoki, J., et al. 1993. Prostaglandins 45, 363.
      Fabbri, E., et al. 1991. J. Enzyme Inhib. 5, 87.
      Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.

      Brochure

      Title
      Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      Synonyms9-(Tetrahydro-2ʹ-furyl)adenine
      DescriptionCell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC50 = 200 µM). Reduces PGE2-induced inhibition of O2·– production.
      FormOff-white solid
      CAS number17318-31-9
      Chemical formulaC₉H₁₁N₅O
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (25 mg/ml) or H₂O (5 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.
      Toxicity Irritant
      ReferencesTalpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
      Tamaoki, J., et al. 1993. Prostaglandins 45, 363.
      Fabbri, E., et al. 1991. J. Enzyme Inhib. 5, 87.
      Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.