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17-300 Ral Activation Assay Kit

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17-300
1 kit  Kit capacity: 30 assays
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      Overview

      Key Spec Table

      Key Applications
      ABA
      Description
      Catalogue Number17-300
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionRal Activation Assay Kit
      Product Information
      Components
      • Ral Activation Assay Buffer, 5X (Cat.# 20-196)
      • 100X GTPγS, 10mM (Cat.# 20-176)
      • 100X GDP, 100mM (Cat.# 20-177)
      • Anti-Ral-A
      • Ral Assay Reagent (Ral BP1, agarose) (Cat.# 14-415)
      Quality LevelMQ100
      Applications
      ApplicationNon-radioactive Ral Activation Assay Kit can be used to precipitate Ral-A-GTP from cell lysates & detection by a Ral-A specific antibody.
      Key Applications
      • Affinity Binding Assay
      Biological Information
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors.
      Gene Symbol
      • RALA
      • RAL
      • MGC48949
      UniProt Number
      UniProt SummarySIZE: 206 amino acids; 23567 Da
      SUBUNIT: Interacts with RALBP1 via its effector domain. Interacts with EXOC8 and EXOC2. EXOC2 and EXOC8 have overlapping binding sites and compete for RALA binding. Interacts with Clostridium exoenzyme C3.
      SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).
      SIMILARITY: SwissProt: P11233 ## Belongs to the small GTPase superfamily. Ras family.
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by affinity precipitation/immunoblot analysis. Ral-A-GTP was precipitated from EGF-stimulated Cos-7 cell lysates. The precipitated Ral-A-GTP was detected by Western immunoblot analysis using anti-Ral A.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Packaging Information
      Material Size1 kit
      Material PackageKit capacity: 30 assays
      Global Trade Item Number
      Catalogue Number GTIN
      17-300 04053252622861