475870 Sigma-AldrichMnTBAP - Calbiochem
MnTBAP, CAS 55266-18-7, is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger.
More>> MnTBAP, CAS 55266-18-7, is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Less<<Synonyms: Mn(III)tetrakis(4-benzoic acid)porphyrin Chloride
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Overview
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Key Spec Table
CAS # | Empirical Formula |
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55266-18-7 | C₄₈H₂₈ClMnN₄O₈ |
Pricing & Availability
Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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475870-25MG |
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Plastic ampoule | 25 mg |
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Description | |
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Overview | Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50 ~40 µM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 (Cat. No. 309825) by peroxynitrite, but does not scavenge nitric oxide (NO). |
Catalogue Number | 475870 |
Brand Family | Calbiochem® |
Synonyms | Mn(III)tetrakis(4-benzoic acid)porphyrin Chloride |
Product Information | |
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CAS number | 55266-18-7 |
ATP Competitive | N |
Form | Brown solid |
Hill Formula | C₄₈H₂₈ClMnN₄O₈ |
Chemical formula | C₄₈H₂₈ClMnN₄O₈ |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications | |
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Application | MnTBAP, CAS 55266-18-7, is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. |
Biological Information | |
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Primary Target | Superoxide dismutase (SOD) mimetic |
Primary Target IC<sub>50</sub> | EC50 ~40 µM in protecting endothelial cells against paraquat (2 mM) |
Purity | ≥95% by TLC |
Physicochemical Information | |
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Cell permeable | Y |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalogue Number | GTIN |
475870-25MG | 07790788050467 |
Documentation
MnTBAP - Calbiochem SDS
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MnTBAP - Calbiochem Certificates of Analysis
Title | Lot Number |
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475870 |
References
Reference overview |
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Aladag, M. A., et al. 2003. Acta Neurochir. 145, 673. Szabo, C., et al. 1996. FEBS Lett. 381, 82. Day, B.J., et al. 1995. J. Pharmacol. Exp. Ther. 275, 1227. Faulkner, K.M., et al. 1994. J. Biol. Chem. 269, 23471. |
Brochure
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Pathways and Biomarkers of Oxidative Stress |
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Data Sheet | ||||||||||||||||||||||||||||||
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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