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FCMAB323PE Milli-Mark™ Anti-Phosphotyrosine-PE Antibody, recombinant clone 4G10®

Milli-Mark Anti-Phosphotyrosine-PE Antibody, recombinant clone 4G10 is an antibody against Phosphotyrosine clone 4G10 for use in FC.

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Research Category: Signaling Research Sub-Category: General Post-translation Modification
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FCMAB323PE
100 tests  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      VrtFCMPhycoerythrinMonoclonal Antibody
      Description
      Catalogue NumberFCMAB323PE
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-Phosphotyrosine-PE Antibody, recombinant clone 4G10®
      Background InformationSome of the tyrosine residues can be tagged with a phosphate group by protein kinases and in its phosphorylated state, it is referred to as phosphotyrosine. Tyrosine phosphorylation is considered as one of the key steps in signal transduction and regulation of enzymatic activity.
      The advent of anti-phosphotyrosine antibodies is one of the significant events in signal transduction research. Before the availability of anti-phosphotyrosine antibodies, tyrosine phosphorylation of proteins and enzymes was investigated through hazardous and time-consuming radioactive experiments. Anti-phosphotyrosine antibodies are commonly used in western blots after the targeted proteins have been immunoprecipitated to measure the tyrosyne phosphorylation of the proteins. Anti-phosphotyrosine antibodies are also directly used on cell lysate to examine the overall change of tyrosine phosphorylation level in reponse to various treatments.
      Product Information
      FormatPhycoerythrin
      Control
      • Treated versus untreated A431 cells
      PresentationPurified mouse monoclonal IgG2bk conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.
      Quality LevelMQ100
      Applications
      ApplicationMilli-Mark Anti-Phosphotyrosine-PE Antibody, recombinant clone 4G10 is an antibody against Phosphotyrosine clone 4G10 for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenPhosphotyramine-KLH
      Clone4G10
      HostMouse
      SpecificityAntibody recognizes tyrosine-phosphorylated proteins from all species
      IsotypeIgG2bκ
      Species Reactivity
      • Vertebrates
      Species Reactivity NoteTested and passed on Human. Expected to detect tyrosyne phosphorylated proteins in all species.
      Antibody TypeMonoclonal Antibody
      Purification MethodProtein G Purified
      Molecular WeightDependent upon the molecular weight of the tyrosine phosphorylated protein being detected.
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using EGF treated versus untreated A431 cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Global Trade Item Number
      Catalogue Number GTIN
      FCMAB323PE 04053252749537