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FCMAB185AP Milli-Mark™ Anti-CD19 -APC Antibody, clone HD37

This Milli-Mark Anti-CD19 -APC Antibody, clone HD37 is validated for use in FC for the detection of CD19 -APC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P15391
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FCMAB185AP
100 tests  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMAPCMonoclonal Antibody
      Description
      Catalogue NumberFCMAB185AP
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD19 -APC Antibody, clone HD37
      Alternate Names
      • Differentiation antigen CD19
        B-lymphocyte surface antigen B4
        T-cell surface antigen Leu-12
      • B-lymphocyte antigen CD19
      Background InformationCD19 is a 120 kDa transmembrane glycoprotein with a reduced MW of 95 kDa (Pezzutto, 1987; Sato, 1997). CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains (Pezzutto, 1987), and it is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation (Sato, 1997). CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes (Pezzutto, 1987). The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells (Pezzutto, 1987).
      Product Information
      FormatAPC
      Control
      • Human Lymphocytes
      PresentationPurified Mouse monoclonal IgG1 conjugated to APC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
      Quality LevelMQ100
      Applications
      ApplicationThis Milli-Mark Anti-CD19 -APC Antibody, clone HD37 is validated for use in FC for the detection of CD19 -APC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenHairy cell leukemia cells
      CloneHD37
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD19 antigen.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight120 kDa (Pezzutto, 1987; Sato, 1997)
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using Human Lymphocytes
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Global Trade Item Number
      Catalogue Number GTIN
      FCMAB185AP 04053252746376