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FCMAB185AP Milli-Mark™ Anti-CD19 -APC Antibody, clone HD37

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FCMAB185AP
100 tests  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMAPCMonoclonal Antibody
      Description
      Catalogue NumberFCMAB185AP
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD19 -APC Antibody, clone HD37
      Alternate Names
      • Differentiation antigen CD19
        B-lymphocyte surface antigen B4
        T-cell surface antigen Leu-12
      • B-lymphocyte antigen CD19
      Background InformationCD19 is a 120 kDa transmembrane glycoprotein with a reduced MW of 95 kDa (Pezzutto, 1987; Sato, 1997). CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains (Pezzutto, 1987), and it is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation (Sato, 1997). CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes (Pezzutto, 1987). The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells (Pezzutto, 1987).
      References
      Product Information
      FormatAPC
      Control
      • Human Lymphocytes
      PresentationPurified Mouse monoclonal IgG1 conjugated to APC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
      Quality LevelMQ100
      Applications
      ApplicationThis Milli-Mark Anti-CD19 -APC Antibody, clone HD37 is validated for use in FC for the detection of CD19 -APC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenHairy cell leukemia cells
      CloneHD37
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD19 antigen.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight120 kDa (Pezzutto, 1987; Sato, 1997)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using Human Lymphocytes
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      FCMAB185AP 04053252746376

      Documentation

      Milli-Mark™ Anti-CD19 -APC Antibody, clone HD37 SDS

      Title

      Safety Data Sheet (SDS) 

      Milli-Mark™ Anti-CD19 -APC Antibody, clone HD37 Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-CD19 -APC, clone HD37 - 1989783 1989783
      Milli-Mark Anti-CD19 -APC, clone HD37 - 2049271 2049271
      Milli-Mark Anti-CD19 -APC, clone HD37 - 2064307 2064307
      Milli-Mark Anti-CD19 -APC, clone HD37 - 2207210 2207210
      Milli-Mark Anti-CD19 -APC, clone HD37 - NRG1761317 NRG1761317
      Milli-Mark™ Anti-CD19 -APC, -2580667 2580667
      Milli-Mark™ Anti-CD19 -APC, -2724438 2724438
      Milli-Mark™ Anti-CD19 -APC, -2772649 2772649
      Milli-Mark™ Anti-CD19 -APC, clone HD37 2475030
      Milli-Mark™ Anti-CD19 -APC, clone HD37 - 2514238 2514238

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies