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105020 L-Leucine

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
61-90-5200-522-0C₆H₁₃NO₂131.17 g/molPh Eur,ChP,JP,USP

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
1050201000
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      Plastic bottle 1 kg
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      1050209010
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          Plastic drum 10 kg
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          Description
          Catalogue Number105020
          SynonymsLeu
          References
          Product Information
          CAS number61-90-5
          EC number200-522-0
          GradePh Eur,ChP,JP,USP
          Hill FormulaC₆H₁₃NO₂
          Molar Mass131.17 g/mol
          HS Code2922 49 90
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Density1.17 g/cm3 (20 °C)
          Melting Point293 °C (decomposition)
          pH value5.5 - 6.5 (20 g/l, H₂O, 20 °C)
          Vapor pressure<1 hPa (20 °C)
          Bulk density300 - 400 kg/m3
          Solubility18.9 g/l
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSOH2850000
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +30°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
          Identity (IR-spectrum)passes test
          Identity (specific rotation)passes test
          Identity (TLC)passes test
          Appearancewhite to almost white, crystalline powder or shiny flakes
          Appearance of solution (50 g/l; hydrochloric acid 1 mol/l)clear and not more intense in color than reference solution BY₆
          Transmittance of solution (10 g/l, water)≥ 98.0 %
          Spec. rotation (α 20/D, 40 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+14.5 to +16.5
          Spec. rotation (α 25/D, 40 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+14.9 to +17.3
          Spec. rotation (α 20/D, 40 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+14.9 to +16.0
          pH (10 g/l, CO₂-free water)5.5 - 6.5
          Acidity (10 g/l, water)5.5 - 6.5
          Chloride (Cl)≤ 200 ppm
          Sulfate (SO₄)≤ 200 ppm
          Heavy metals (as Pb)≤ 10 ppm
          Fe (Iron)≤ 10 ppm
          As (Arsenic)≤ 1 ppm
          Other amino acids (TLC)≤ 0.5 %
          Related Compounds, total (TLC)≤ 0.5 %
          Related substances (TLC)passes test
          Related compounds (HPLC) (Isoleucine)≤ 0.8 %
          Related compounds (HPLC) (Any unspecified impurity)≤ 0.2 %
          Related compounds (HPLC) (Total unspecified impurities)≤ 1.0 %
          Ninhydrin-positive substances (LC) (impurity A (570 nm))≤ 0.8 %
          Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
          Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
          Ninhydrin-positive substances (LC) (total impurities)≤ 1.0 %
          Residual solvents (ICH Q3C)excluded by manufacturing process
          Sulfated ash (600 °C)≤ 0.1 %
          Loss on drying (105 °C; 3 h)≤ 0.20 %
          Bacterial endotoxins≤ 3.0 I.U./g
          Microbiological test (total aerobic microbial count (TAMC))≤ 10²
          Microbiological test (total yeast and mould count (TYMC))≤ 10¹
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph. Eur., JP, USP
          Global Trade Item Number
          Catalogue Number GTIN
          1050201000 04022536986364
          1050209010 04022536986098

          Documentation

          Material Qualification Dossier

          TitleVersion
          9.0

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          L-Leucine SDS

          Title

          Safety Data Sheet (SDS) 

          L-Leucine Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1050201000 Plastic bottlePDF Specification Document
          1050209010 Plastic drumPDF Specification Document

          Certificates

          Title